We are a human-sized, international, and independent pharmaceutical group, governed by a Foundation. Our unique model is a source of pride, but above all, it allows us to fully serve our mission: “Committed to therapeutic progress for the benefit of patients.”
Today, a global leader in cardiology, we have chosen to become a focused and innovative player in oncology by 2030, targeting hard-to-treat cancers and dedicating more than 70% of our R&D budget to this area. We are committed to equal opportunities and the development of talent in all its diversity. We value both experience and the willingness to engage daily to contribute to therapeutic progress for the benefit of patients. If you see yourself reflected in this offer and these few lines, seize the opportunity to meet us. We pursue this challenge alongside the development of our generics business, ensuring access to quality care for all, at a lower cost.
Who are we? 22,000 passionate individuals from over 50 nationalities, driven by an entrepreneurial spirit. Every day, we move forward with and for patients, with and for our teams, guided by the desire to care, to take risks, to grow, and to commit ourselves to be useful to those in need.
Come experience and help bring our commitment to life: #MovedByYou
www.servier.com
Biomarker Strategy Leader Oncology
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About our R&D Institute in Paris Saclay:**
At the heart of one of the world's top eight innovation clusters, the Servier R&D Institute at Paris-Saclay is where visionary science meets a powerful global ecosystem. By uniting our Group's innovation potential with this prestigious center of excellence, we are not only accelerating the future of therapeutic discovery but also championing the global influence of French research.
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About the role:**
Within the clinical development biomarker oncology team in the Translational Medicine structure, you will have the responsibility to identify and develop biomarkers to increase projects’ probability of success by selecting the right population benefiting from the treatment and to supporting the validation of the proof of mechanism and the best efficacy/safety ratio. You may be also in charge of defining and setting up human experimental studies aiming at increasing our ability and knowledge on “targeted population” to improve projects probability of success.
Your main responsibilities:
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Lead the biomarker plan strategy to support the clinical development from Lead Optimization to Life Cycle Management stages
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Be a member of the project team and of the core-team according to project stage and could participate to meetings with partners, experts & health authorities
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Contribute to indications selection, to identification of sub-populations & drug combinations based on project needs to guide the clinical development plan
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Contribute to define criteria for project decision supported by biomarker data in close collaboration with clinical and biostatistics teams
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Coordinate in link with the pharmacologist as well as technical expert teams the generation of in vitro/in vivo/ex vivo data to identify/confirm biomarker hypotheses
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Contribute to the design of pharmacological studies
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Provide interpretation of biomarker data with biostatistics, modeling, clinical pharmacology and clinician
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Write the biomarker part of the internal and regulatory documents
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Enrich the Biomarker related knowledge of pathologies related to oncology
What we’re looking for :
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Background: Scientific initial training (PhD in Life Sciences +/- Post-doc, PharmD, MD) and in-depth knowledge in oncology. Ideally 1-3 years experience in pharmaceutical or biotech industry
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Hard Skills :
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Expertise in oncology and understanding pathophysiology
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Experience in translational research and biomarker strategies
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Knowledge in drug development and clinical trial methodologies
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Language skills : Fluent in English, French is a plus
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Soft skills:
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Strong collaborative spirit, eagerness to share knowledge and expertise within the team
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Capability to work in matrixial organization with other expertise
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Innovative, able to challenge status quo
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Good communication skills, ability to convince and be challenged
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High commitment to bring innovative medicine to patients with unmet needs
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Problem-solving oriented
**What We Offer:
**A dynamic and supportive environment with:
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23 RTT days + 27 vacation days per year
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Teleworking possibility based on the position
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Performance-related and profit-sharing bonuses
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Premium health insurance and welfare coverage
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Numerous employee benefits (vouchers, bonuses, cultural and sports discounts)
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Modern facilities, subsidized restaurant, and gym access at some sites
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Certified Top Employer (France & Europe) for 3 years running
We are committed to equal opportunities and the development of talent in all its diversity. We value both experience and the willingness to engage daily to contribute to therapeutic progress for the benefit of patients. If you see yourself reflected in this offer and these few lines, seize the opportunity to meet us.